Directed Evolution Using Stabilized Bacterial Peptide Display
نویسندگان
چکیده
منابع مشابه
Directed evolution of a biterminal bacterial display scaffold enhances the display of diverse peptides
Bacterial cell-surface display systems coupled with quantitative screening methods offer the potential to expand protein engineering capabilities. To more fully exploit this potential, a unique bacterial surface display scaffold was engineered to display peptides more efficiently from the surface exposed C- and N-termini of a circularly permuted outer membrane protein. Using directed evolution,...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2019
ISSN: 0002-7863,1520-5126
DOI: 10.1021/jacs.9b10716